An AI Digital Cell Clone™ Factory

ThinkingNode.Life (TNL) is the first AI techbio company to develop Large Reasoning Models™ (LRM) to generate digital cell simulations capable of revolutionizing biology.

Applied to drug R&D, TNL's Digital Cell Clone™ platform can produce the most advanced human digital cell simulations in less than an hour, which can be used to predict and understand cellular behavior and response to drugs for safety, efficacy, and specificity.

As the cell is the fundamental unit of biology, TNL can create value at multiple points throughout the entire drug R&D process. Unlike most AI drug R&D companies that focus only on drug design, TNL simulates cellular responses to drugs before and after each stage of pharmaceutical R&D to de-risk by providing critical insights for decision-making. TNL's Digital Cell Clones have been used for novel target discovery, target validation, biomarker discovery, indication expansion, drug combination, drug comparison, drug response prediction, mechanism of action validation, and patient stratification.

TNL’s Large Reasoning Models™ (LRM) have been created based on Generative Macro-connectionist Reasoning AI (GMR-AI), the second generation of Dr. Pham's Distributed Reasoning AI. The first generation was successfully used in his first AI company (acquired by Nasdaq: EPNY for $637M). The LRMs are built on extensive knowledge bases characterizing cellular structure and function, and then further refined with gene expression data through a proprietary process, called Digital Cell Differentiation™, to produce specific Digital Cell Clones of interest. The result is highly unique, powerful cell simulations which are capable of predicting dynamic cellular responses in an unprecedented, scalable digital platform.